Stoneman Syndrome

Stoneman syndrome or fibrodysplastic ossificans progressiva (FOP) or Munchmeyer's disease is a rare genetic disease of ectopic soft tissue calcification with hand and foot deformities leading to severe restriction of joint movements. It was first described in 1692 in a young patient who turned into wood. It may be sporadic or autosomal dominant. The disease is caused by mutation in the bone morphogenic protein

The incidence, as reported from Europe and United States, is around 1 in two million individuals.. There are a few case reports from the Indian subcontinent.